Derma E, acne spot treatment, very clear is eco-ethical. This product is an anti-blemish complex and can be used to treat problem acne spots and comes in a 0.5 oz. box. Derma e, acne spot treatment, very clear should be kept out of the reach of children. Skin irritation and dryness is more likely to occur if another topical acne medication is used with this product at the same time. Derma e, acne spot treatment, very clear is 100% vegan, cruelty-free and does not contain gluten, soy or GMO’s.